Hokkaido University Divison of Applied Chemistry Chemical Process Engineering

Laboratory of Organic Reaction
Structural Organic Chemistry Group

Recent Publications

  1. Luminescent Coordination Polymers Constructed from Flexible, Tetradentate Diisopyrazole Ligand and Copper(I) Halides
  2. T. Yoneda, C. Kasai, Y. Manabe, M. Tsurui, Y. Kitagawa, Y. Hasegawa, P. Sarkar, Y. Inokuma

    Chem. Asian J., 2020, accepted.


    Luminescent coordination polymers generated from an aliphatic imine ligand and Cu(I) halides. Thermochromic behavior was observed for 2-dimensional Cu4I4 cluster network.

  3. Splitting and Reorientation of π-Conjugation by an Unprecedented Photo-Rearrangement Reaction
  4. Y. Inaba, T. Yoneda, Y. Kitagawa, K. Miyata, Y. Hasegawa, Y. Inokuma

    Chem. Commun., 2020, 56, 348-351.


    Nobel photo-induced rearrangement reaction for splitting π-conjugation of polyene. (Selected as Back Cover)

  5. Identification of Actinomycin D as a Specific Inhibitor of the Alternative Pathway of Peptidoglycan Biosynthesis
  6. Y. Ogasawara, Y. Shimizu, Y. Sato, T. Yoneda, Y. Inokuma, T. Dairi

    J. Antibiot., 2020, 73, 125-127.


    A joint paper with Dr. Ogasawara and Prof. Dairi.

  7. Asymmetric Synthesis of a 5,7-Fused Ring System Enabled by an Intramolecular Buchner Reaction with Chiral Rhodium Catalyst
  8. T. Hoshi, E. Ota, Y. Inokuma, J. Yamaguchi

    Org. Lett., 2019, 21, 10081-10084.


    A joint paper with Prof. Yamaguchi (Waseda Univ.).

  9. Aliphatic Polyketones as Shapable Molecular Chains
  10. Y. Inokuma

    J. Synth. Org. Chem. Jpn., 2019, 77, 1078-1085.


    An account of carbonyl ropes.

  11. Two-Step Transformation of Aliphatic Polyketones into π-Conjugated Polyimines
  12. Y. Manabe, M. Uesaka, T. Yoneda, Y. Inokuma

    J. Org. Chem., 2019, 84, 9957-9964.


    Carbonyl ropes were converted into highly π-conjugated imine 'sashes'. (Selected as Cover Picture)

  13. Control over Coordination Self-Assembly of Flexible, Multidentate Ligands by Stepwise Metal Coordination of Isopyrazole Subunits
  14. Y. Ashida, Y. Manabe, S. Yoshioka, T. Yoneda, Y. Inokuma

    Dalton Trans., 2019, 48, 818-822.


    Self-assembly of oligoimine chains by the aid of stepwise palladium ion coordination. (Selected as Inside Back Cover)

  15. Bioinspired Synthesis of Pentalene-based Chromophores from an Oligoketone Chain
  16. Y. Saito, M. Higuchi, S. Yoshioka, H. Senboku, Y. Inokuma

    Chem. Commun., 2018, 54, 6788-6791.


    Folding a carbonyl string to make chromophores that absorb and emit visible light.

  17. Oligoacetylacetones as Shapable Carbon Chains and Their Transformation to Oligoimines for Construction of Metal-organic Architectures
  18. M. Uesaka, Y. Saito, S. Yoshioka, Y. Domoto, M. Fujita, Y. Inokuma

    Communications Chemistry, 2018, 1, Article Number 23.


    Our first paper from Hokkaido University!! The concept, synthesis and transformation of polycarbonyl chains are reported.

    Behind the Paper (Nature Research Chemistry Community)

  19. Chiral Crystalline Sponges for the Absolute Structure Determination of Chiral Guests
  20. K. Yan, R. Dubey, T. Arai, Y. Inokuma, M. Fujita

    J. Am. Chem. Soc. 2017, 139, 11341-11344.

  21. Structural Elucidation of Trace Amounts of Volatile Compounds Using the Crystalline Sponge Method
  22. N. Zigon, T. Kikuchi, J. Ariyoshi, Y. Inokuma, M. Fujita

    Chem. Asian J. 2017, 12, 1057-1061.

  23. Finding a New Crystalline Sponge from a Crystallographic Database
  24. Y. Inokuma, K. Matsumura, S. Yoshioka, M. Fujita

    Chem. Asian. J. 2017, 12, 208-211. (Front Cover)

  25. X-ray Structure Analysis of Ozonides by the Crystalline Sponge Method
  26. S. Yoshioka, Y. Inokuma, V. Duplan, R. Dubey, M. Fujita

    J. Am. Chem. Soc. 2016, 138, 10140-10142.

  27. A Saccharide-based Crystalline Sponge for Hydrophilic Guests
  28. G.-H. Ning, K. Matsumura, Y. Inokuma, M. Fujita

    Chem. Commun. , 2016, 52, 7013-7015.

  29. Structure Determination of Microbial Metabolites by the Crystalline Sponge Method
  30. Y. Inokuma, T. Ukegawa, M. Hoshino, M. Fujita

    Chem. Sci. 2016, 7, 3910-3913.

  31. The Crystalline Sponge Method Updated
  32. M. Hoshino, A. Khutia, H. Xing, Y. Inokuma, M. Fujita

    IUCrJ 2016, 3, 139-151.

  33. Where is the Oxygen? Structural Analysis of a-Humulene Oxidation Products by the Crystalline Sponge Method
  34. N. Zigon, M. Hoshino, S. Yoshioka, Y. Inokuma, M. Fujita

    Angew. Chem. Int. Ed. 2015, 54, 9033-9037.

  35. Absolute Structure Determination of Compounds with Axial and Planar Chirality Using the Crystalline Sponge Method
  36. S. Yoshioka, Y. Inokuma, M. Hoshino, T. Sato, M. Fujita

    Chem. Sci. 2015, 6, 3765-3768.

  37. Networked-Cage Microcrystals for Evaluation of Host-guest Interactions
  38. S. Matsuzaki, T. Arai, K. Ikemoto, Y. Inokuma, M. Fujita

    J. Am. Chem. Soc. 2014, 136, 17899-17901.

  39. Visualization of Solution Chemistry by X-ray Crystallography Using Porous Coordination Networks
  40. Y. Inokuma, M. Fujita

    Bull. Chem. Soc. Jpn. 2014, 87, 1161-1176.

    (Award Article, Back Cover)

  41. Radical C-H Functionalization of Heteroarenes under Electrochemical Control
  42. A. O'Brien, A. Maruyama, Y. Inokuma, M. Fujita, P. S. Baran, D. G. Blackmond

    Angew. Chem. Int. Ed. 2014, 53, 11868-11871.

    (Selected as a Hot Paper)

  43. X-ray Snapshot Observation of Palladium-Mediated Aromatic Bromination in a Porous Complex
  44. K. Ikemoto, Y. Inokuma, K. Rissanen, M. Fujita

    J. Am. Chem. Soc. 2014, 136, 6892-6895.

    (Highlighted by "Chemistry World", RSC)

  45. Preparation and Guest-uptake Protocol for a Porous Complex Useful for 'Crystal-free' Crystallography
  46. Y. Inokuma, S. Yoshioka, J. Ariyoshi, T. Arai, M. Fujita

    Nature Protocols 2014, 9, 246-252.

  47. Stable Encapsulation of Acrylate Esters in Networked Molecular Capsules
  48. G.-H Ning, Y. Inokuma, M. Fujita

    Chem. Asian J. 2014, 9, 466-468.

    (VIP paper, Inside Cover)

  49. Unique Ultrafast Energy Transfer in a Series of Phenylene-bridged Subporphyrin-porphyrin Hybrids
  50. J. Oh, J. Sung, M. Kitano, Y. Inokuma, A. Osuka, D. Kim

    Chem. Commun. 2014, 50, 10424-10426.

  51. Dynamic Behavior of M6L4 Capsules in Solution and Crystalline States
  52. G.-H Ning, Y. Inokuma, M. Fujita

    Chem. Asian J. 2013, 8, 2596-2599.

  53. X-ray analysis on the nanogram to microgram scale using porous complexes
  54. Y. Inokuma, S. Yoshioka, J. Ariyoshi, T. Arai, Y. Hitora, K. Takada, S. Matsunaga, K. Rissanen, M. Fujita

    Nature 2013, 495, 461-466.

    (Highlighted by "Nature news and views" )

    (Highlighted by "C&EN", ACS)

    (Highlighted by "Chemistry World", RSC)

  55. Reagent-Installed Capsule Network: Selective Thiocarbamoylation of Aromatic Amines in Crystals with Pre-installed CH3NCS
  56. Y. Inokuma, G.-H. Ning, M. Fujita

    Angew. Chem. Int. Ed. 2012, 51, 2379-2381.

  57. Oxocyclohexadienylidene-Substituted Subporphyrins
  58. S. Hayashi, J. Sung, Y. Sung, Y. M. Sung, Y. Inokuma, D. Kim, A. Osuka

    Angew. Chem. Int. Ed. 2011, 50, 3253-3256.

  59. Bimolecular Reaction via the Successive Introduction of Two Substrates into the Crystals of Networked Molecular Cages
  60. Y. Inokuma, N. Kojima, T. Arai, M. Fujita

    J. Am. Chem. Soc. 2011, 133, 19691-19693.

  61. Diels-Alder via Molecular Recognition in a Crystalline Molecular Flask
  62. K. Ikemoto, Y. Inokuma, M. Fujita

    J. Am. Chem. Soc. 2011, 133, 16806-16808.

  63. Shedding Light on Hidden Reaction Pathways in Radical Polymerization by a Porous Coordination Network
  64. Y. Inokuma, S. Nishiguchi, K. Ikemoto, M. Fujita

    Chem. Commun. 2011, 47, 12113-12115.

  65. Synthesis and Properties of Boron(III)-Coordinated Subbacteriochlorins
  66. S. Hayashi, E. Tsurumaki, Y. Inokuma, P. Kim, Y. M. Sung, D. Kim, A. Osuka

    J. Am. Chem. Soc. 2011, 133, 4254-4256.

  67. Crystalline Molecular Flasks
  68. Y. Inokuma, M. Kawano, M. Fujita

    Nature Chem. 2011, 3, 349-358.

  69. A Molecular Capsule Network: Guest Encapsulation and Control of Diels-Alder Reactivity
  70. Y. Inokuma, S. Yoshioka, M. Fujita

    Angew. Chem. Int. Ed. 2010, 49, 8912-8914.

  71. Networked Molecular Cages as Crystalline Sponges for Fullerenes and Other Guests
  72. Y. Inokuma, T. Arai, M. Fujita

    Nature Chem. 2010, 2, 780-783.

    (Highlighted by "C&EN", ACS)

  73. The Reaction of Organozinc Compounds with an Aldehyde within a Crystalline Molecular Flask
  74. K. Ikemoto, Y. Inokuma, M. Fujita

    Angew. Chem. Int. Ed. 2010, 49, 5750-5752.

  75. The Catalytic Z to E Isomerization of Stilbenes in a Photosensitizing Porous Coordination Network
  76. K. Ohara, Y. Inokuma, M. Fujita

    Angew. Chem. Int. Ed. 2010, 49, 5507-5509.

  77. Regioselective Huisgen Cycloaddition within Porous Coordination Networks
  78. T. Kawamichi, Y. Inokuma, M. Fujita

    Angew. Chem. Int. Ed. 2010, 49, 2375-2377.

    (Highlighted by "Noteworthy Chemistry", ACS)

  79. A Porous Coordination Network Catalyzes an Olefin Isomerization Reaction in the Pore
  80. K. Ohara, M. Kawano, Y. Inokuma, M. Fujita

    J. Am. Chem. Soc. 2010, 132, 30-31.

  81. meso-Tris(oligo-2,5-thienylene)-Substituted Subporphyrins
  82. S. Hayashi, Y. Inokuma, A. Osuka

    Org. Lett. 2010, 12, 4148-4151.

  83. meso-Trifluoromethyl-substituted Subporphyrin from Ring-splitting Reaction of meso-Trifluoromethyl-substituted [32]Heptaphyrin(
  84. R. Sakamoto, S. Saito, S. Shimizu, Y. Inokuma, N. Aratani, A. Osuka

    Chem. Lett. 2010, 39, 439-441.

  85. meso-Trialkyl-substituted Subporphyrins
  86. S. Hayashi, Y. Inokuma, S. Easwaramoorthi, K. S. Kim, D. Kim, A. Osuka

    Angew. Chem. Int. Ed. 2010, 49, 321-324.

  87. Versatile Photophysical Properties of meso-Aryl Substituted Subporphyrins: Dipolar and Octupolar Charge-Transfer Interactions
  88. S. Easwaramoorthi, J.-Y. Shin, S. Cho, P. Kim, Y. Inokuma, E. Tsurumaki, A. Osuka, D. Kim

    Chem. Eur. J. 2009, 15, 12005-12017.

  89. Capped Subporphyrins
  90. Y. Inokuma, A. Osuka

    Chem. Eur. J. 2009, 15, 6863-6876.

  91. 1,4-Phenylene-bridged Subporphyrin-porphyrin Dyad, Triad, and Tetrad
  92. Y. Inokuma, S. Hayashi, A. Osuka

    Chem. Lett. 2009, 38, 206-207.

  93. Peripheral Hexabromination, Hexaphenylation, and Hexaethynylation of meso-Aryl- Substituted Subporphyrins
  94. E. Tsurumaki, Y. Inokuma, S. Easwaramoorthi, J. M. Lim, D. Kim, A. Osuka

    Chem. Eur. J. 2009, 15, 237-247.

  95. 3,3- and 4,4-Biphenylene-Bridged Subporphyrin Dimers
  96. Y. Inokuma, A. Osuka

    Org. Lett. 2008, 10, 5561-5564.

  97. Unambiguous Identification of Möbius Aromaticity for meso-Aryl-Substituted [28]Hexaphyrins(
  98. J. Sankar, S. Mori, S. Saito, H. Rath, M. Suzuki, Y. Inokuma, H. Shinokubo, K. S. Kim, Z. S. Yoon, J.-Y. Shin, J. M. Lim, Y. Matsuzaki, O. Matsushita, A. Muranaka, N. Kobayashi, D. Kim A. Osuka

    J. Am. Chem. Soc. 2008, 130, 13568-13579.

  99. meso-(4-(N,N-Dialkylamino)phenyl)-Substituted Subporphyrins: Remarkably Perturbed Absorption Spectra and Enhanced Fluorescence by Intramolecular Charge Transfer Interactions
  100. Y. Inokuma, S. Easwaramoorthi, Z. S. Yoon, D. Kim, A. Osuka

    J. Am. Chem. Soc. 2008, 130, 12234-12235.

  101. Effective Expansion of the Subporphyrin Chromophore Through Conjugation with meso-Oligo(1,4-phenyleneethynylene) Substituents: Octupolar Effect on Two-Photon Absorption
  102. Y. Inokuma, S. Easwaramoorthi, S. Y. Jang, K. S. Kim, D. Kim, A. Osuka

    Angew. Chem. Int. Ed. 2008, 47, 4840-4843.

  103. Subporphyrins: Emerging Contracted Porphyrins with Aromatic 14π-Electronic Systems and Bowl-Shaped Structures: Rational and Unexpected Synthetic Routes
  104. Y. Inokuma, A. Osuka

    Dalton Trans. 2008, 2517-2526. (Perspective, Front Cover)

  105. Synthesis and Characterization of meso-Aryl-Substituted Subchlorins
  106. E. Tsurumaki, S. Saito, K. S. Kim, J. M. Lim, Y. Inokuma, D. Kim, A. Osuka

    J. Am. Chem. Soc. 2008, 130, 438-439.

  107. Complementary Face-to-Face Dimer Formation From meso-Aryl Subporphyrins Bearing a 2-Carboxyphenyl Group
  108. Y. Inokuma, A. Osuka

    Chem. Commun. 2007, 2938-2940.

  109. meso-Aryl-Substituted Subporphyrins: Synthesis, Structures, and Large Substituent Effects on Their Electronic Properties
  110. Y. Inokuma, Z. S. Yoon, D. Kim, A. Osuka

    J. Am. Chem. Soc. 2007, 129, 4747-4761.

  111. Tribenzosubporphines: Synthesis and Characterization
  112. Y. Inokuma, J. H. Kwon, T. K. Ahn, M.-C. Yoon, D. Kim, A. Osuka

    Angew. Chem. Int. Ed. 2006, 45, 961-964.

  113. Enlarged π-Electronic Network of a meso-meso, β-β, β-β Triply Linked Dibenzoporphyrin Dimer that Exhibits a Large Two-Photon Absorption Cross Section
  114. Y. Inokuma, N. Ono, H. Uno, D. Y. Kim, S. B. Noh, D. Kim, A. Osuka

    Chem. Commun. 2005, 3782-3784.

  115. A Doubly N-Fused Benzohexaphyrin and Its Rearrangement to a Fluorescent Macrocycle upon DDQ Oxidation
  116. Y. Inokuma, T. Matsunari, N. Ono, H. Uno, A. Osuka

    Angew. Chem. Int. Ed. 2005, 44, 1856-1860.

  117. meso-Porphyrinyl-Substituted Porphyrin and Expanded Porphyrins
  118. Y. Inokuma, A. Osuka

    Org. Lett. 2004, 6, 3663-3666.