北海道大学大学院工学研究院 応用化学部門 有機工業化学分野

反応有機化学研究室 構造有機グループ

最近の発表論文

  1. Hybrid Eu(III) Coordination luminophore Standing on Silica Nanoparticles by Two Legs for Enhanced Luminescence
  2. T. Zhang, Y. Kitagawa, R. Moriake, P. P. F. Rosa, M. J. Islam, T. Yoneda, Y. Inokuma, K. Fushimi, Y. Hasegawa

    Chem. Eur. J., 2021, 27, 14438–14443.

    TOC

    同学科の長谷川先生との共著論文です。配位子の合成をお手伝いさせて頂きました。

  3. Calix[3]pyrrole: A Missing Link in Porphyrin-Related Chemistry
  4. Y. Inaba, Y. Nomata, Y. Ide, J. Pirillo, Y. Hijikata, T. Yoneda, A. Osuka, J. L. Sessler, Y. Inokuma

    J. Am. Chem. Soc., 2021, 143, 12355-12360.

    TOC

    14年越しの夢、ついに叶う! カルボニルひもからcalix[3]pyrroleの合成に成功。

    Science誌の"In Other Journals"にてハイライトされました。


    Synfactsにてハイライトされました。


    プレスリリースは、こちら。   

  5. Isopyrazole-Masked Tetraketone: Tautomerism and Functionalization for Fluorescent Metal Ligands
  6. H. Shirakura, Y. Manabe, C. Kasai, Y. Inaba, M. Tsurui, Y. Kitagawa, Y. Hasegawa, T. Yoneda, Y. Ide, Y. Inokuma

    Eur. J. Org. Chem., 2021, 4345–4349.

    TOC

    "マスク"をしたカルボニルひもで、発光性分子が出来ました。

  7. Polyketone-Based Molecular Ropes as Versatile Components for Functional Materials
  8. Y. Inokuma, Y. Inaba

    Bull. Chem. Soc. Jpn., 2021, 94, 2187-2194.

    TOC

    カルボニルひもを使った機能性分子への展開についてAccountを発表しました。

  9. Insoluble π‐Conjugated Polyimine as an Organic Adsorbent for Group 10 Metal Ions
  10. H. Shirakura, Y. Hijikata, J. Pirillo, T. Yoneda, Y. Manabe, M. Murugavel, Y. Ide, Y. Inokuma

    Eur. J. Inorg. Chem., 2021, 1705-1708.

    TOC

    カルボニルひもから誘導される共役ポリイミン化合物に金属吸着の性質が見つかりました。

  11. Aliphatic Polyketones as Classic yet New Molecular Ropes for Structural Diversity in Organic Synthesis
  12. Y. Inokuma, T. Yoneda, Y. Ide, S. Yoshioka

    Chem. Commun., 2020, 56, 9079-9093.

    TOC

    カルボニルひもの概念と脂肪族ポリケトンの合成と反応性に関するFeature Articleを発表しました。

  13. Spirosilicate Dimers of a Bowl-shaped Diol Generated by Intramolecular Cyclization of an Aliphatic Tetraketone Chains
  14. Y. Inaba, Y. Inokuma

    Chem. Lett., 2020, 49, 882-884.

    TOC

    カルボニルひもを使って加水分解に対し安定なスピロシリケートを合成しました。

  15. Modular Synthesis of Oligoacetylacetones via Site-selective Silylation of Acetylacetone Derivatives
  16. P. Sarkar, Y. Inaba, H. Shirakura, T. Yoneda, Y. Inokuma

    Org. Biomol. Chem., 2020, 18, 3297-3302.

    TOC

    モジュール式合成により様々なシークエンスのカルボニルひもを合成しました。

      

  17. Supramolecular Conformational Control of Aliphatic Oligoketones by Rotaxane Formation
  18. Y. Manabe, K. Wada, Y. Baba, T. Yoneda, T. Ogoshi, Y. Inokuma

    Org. Lett., 2020, 22, 3224-3228.

    TOC

    カルボニルひもをピラー[5]アレーンに通してロタキサンを合成しました。京大・生越研究室とのコラボレーションで生まれた成果です。

  19. Chiral Monolayers with Achiral Tetrapod Molecules on Highly Oriented Pyrolytic Graphite
  20. H. Asakawa, S. Matsui, Q. T. Trinh, H. Hirao, Y. Inokuma, T. Ogoshi, S. Tanaka, K. Komatsu, A. Ohta, T. Asakawa, T. Fukuma

    J. Phys. Chem. C, 2020, 124, 7760-7767.

    TOC

    HOPG上にテトラポッド型分子がキラル配列する現象をAFMで観測しました。さきがけ「超空間領域」メンバーの淺川先生、平尾先生、生越先生、そして、金沢大WPI Nano-LSI 福間拠点長をはじめとするメンバーとの共著論文です。

  21. Polyketones as Host Materials for Solid Polymer Electrolytes
  22. T. Eriksson, A. Mace, Y. Manabe, M. Yoshizawa-Fujita, Y. Inokuma, D. Brandell, J. Mindemark

    J. Electrochem. Soc., 2020, 167, 070537.

    TOC

    カルボニルひもがリチウムイオン伝導材料として応用可能であることが、スウェーデン・ウプサラ大、上智大との国際共同研究により明らかとなりました。

  23. Luminescent Coordination Polymers Constructed from Flexible, Tetradentate Diisopyrazole Ligand and Copper(I) Halides
  24. T. Yoneda, C. Kasai, Y. Manabe, M. Tsurui, Y. Kitagawa, Y. Hasegawa, P. Sarkar, Y. Inokuma

    Chem. Asian J., 2020, 15, 601-605.

    TOC

    イミンひもとハロゲン化銅(I)から発光性配位高分子を合成しました。特に、ヨウ化銅から得られた錯体は、サーモクロミズムを示しました。ICReDDの北川先生、長谷川先生との共著論文です。Front Coverに採択されました。

  25. Splitting and Reorientation of π-Conjugation by an Unprecedented Photo-Rearrangement Reaction
  26. Y. Inaba, T. Yoneda, Y. Kitagawa, K. Miyata, Y. Hasegawa, Y. Inokuma

    Chem. Commun., 2020, 56, 348-351.

    TOC

    カルボニルひもから誘導したポリエンのπ共役を光で切断し、並べ替える新転位反応を発見しました。ICReDDの北川先生、長谷川先生、そして九大の宮田先生との共同研究論文です。Back Coverに採択されました!

  27. Identification of Actinomycin D as a Specific Inhibitor of the Alternative Pathway of Peptidoglycan Biosynthesis
  28. Y. Ogasawara, Y. Shimizu, Y. Sato, T. Yoneda, Y. Inokuma, T. Dairi

    J. Antibiot., 2020, 73, 125-127.

    TOC

    同学科の小笠原先生、大利先生との共著論文です。Actinomycin Dの結晶構造解析をお手伝いさせて頂きました。

  29. Asymmetric Synthesis of a 5,7-Fused Ring System Enabled by an Intramolecular Buchner Reaction with Chiral Rhodium Catalyst
  30. T. Hoshi, E. Ota, Y. Inokuma, J. Yamaguchi

    Org. Lett., 2019, 21, 10081-10084.

    TOC

    早稲田大学の山口潤一郎先生との共著論文です。不斉合成した生成物の結晶構造解析をお手伝いさせて頂きました。

  31. Aliphatic Polyketones as Shapable Molecular Chains
  32. Y. Inokuma

    J. Synth. Org. Chem. Jpn., 2019, 77, 1078-1085.

    TOC

    カルボニルひもに関する総合論文です。

  33. Two-Step Transformation of Aliphatic Polyketones into π-Conjugated Polyimines
  34. Y. Manabe, M. Uesaka, T. Yoneda, Y. Inokuma

    J. Org. Chem., 2019, 84, 9957-9964.

    TOC

    カルボニルひもからπ共役イミン色素の帯ができました。カバーピクチャにも採択されました。

  35. Control over Coordination Self-Assembly of Flexible, Multidentate Ligands by Stepwise Metal Coordination of Isopyrazole Subunits
  36. Y. Ashida, Y. Manabe, S. Yoshioka, T. Yoneda, Y. Inokuma

    Dalton Trans., 2019, 48, 818-822.

    TOC

    イミンひもをパラジウムイオンとの段階的錯形成を用いて自己集合させることに成功しました。本論文に関連してInside Back Coverに採択されました。

  37. Bioinspired Synthesis of Pentalene-based Chromophores from an Oligoketone Chain
  38. Y. Saito, M. Higuchi, S. Yoshioka, H. Senboku, Y. Inokuma

    Chem. Commun., 2018, 54, 6788-6791.

    TOC

    カルボニルひもを折り畳んで固体発光を示す色素に変換した研究です。

  39. Oligoacetylacetones as Shapable Carbon Chains and Their Transformation to Oligoimines for Construction of Metal-organic Architectures
  40. M. Uesaka, Y. Saito, S. Yoshioka, Y. Domoto, M. Fujita, Y. Inokuma

    Communications Chemistry, 2018, 1, Article Number 23.

    TOC

    カルボニルひも化合物のコンセプト、合成、分子集合体への応用を報告した猪熊グループ初の論文です。

    北海道大学のプレスリリースは、こちら。 JST版は、こちら。

    Behind the Paper (Nature Research Chemistry Community)の紹介記事

  41. Chiral Crystalline Sponges for the Absolute Structure Determination of Chiral Guests
  42. K. Yan, R. Dubey, T. Arai, Y. Inokuma, M. Fujita

    J. Am. Chem. Soc. 2017, 139, 11341-11344.

  43. Structural Elucidation of Trace Amounts of Volatile Compounds Using the Crystalline Sponge Method
  44. N. Zigon, T. Kikuchi, J. Ariyoshi, Y. Inokuma, M. Fujita

    Chem. Asian J. 2017, 12, 1057-1061.

  45. Finding a New Crystalline Sponge from a Crystallographic Database
  46. Y. Inokuma, K. Matsumura, S. Yoshioka, M. Fujita

    Chem. Asian. J. 2017, 12, 208-211. (Front Cover)

  47. X-ray Structure Analysis of Ozonides by the Crystalline Sponge Method
  48. S. Yoshioka, Y. Inokuma, V. Duplan, R. Dubey, M. Fujita

    J. Am. Chem. Soc. 2016, 138, 10140-10142.

  49. A Saccharide-based Crystalline Sponge for Hydrophilic Guests
  50. G.-H. Ning, K. Matsumura, Y. Inokuma, M. Fujita

    Chem. Commun. 2016, 52, 7013-7015.

  51. Structure Determination of Microbial Metabolites by the Crystalline Sponge Method
  52. Y. Inokuma, T. Ukegawa, M. Hoshino, M. Fujita

    Chem. Sci. 2016, 7, 3910-3913.

  53. The Crystalline Sponge Method Updated
  54. M. Hoshino, A. Khutia, H. Xing, Y. Inokuma, M. Fujita

    IUCrJ 2016, 3, 139-151.

  55. Where is the Oxygen? Structural Analysis of a-Humulene Oxidation Products by the Crystalline Sponge Method
  56. N. Zigon, M. Hoshino, S. Yoshioka, Y. Inokuma, M. Fujita

    Angew. Chem. Int. Ed. 2015, 54, 9033-9037.

  57. Absolute Structure Determination of Compounds with Axial and Planar Chirality Using the Crystalline Sponge Method
  58. S. Yoshioka, Y. Inokuma, M. Hoshino, T. Sato, M. Fujita

    Chem. Sci. 2015, 6, 3765-3768.

  59. Networked-Cage Microcrystals for Evaluation of Host-guest Interactions
  60. S. Matsuzaki, T. Arai, K. Ikemoto, Y. Inokuma, M. Fujita

    J. Am. Chem. Soc. 2014, 136, 17899-17901.

  61. Visualization of Solution Chemistry by X-ray Crystallography Using Porous Coordination Networks
  62. Y. Inokuma, M. Fujita

    Bull. Chem. Soc. Jpn. 2014, 87, 1161-1176.

    (Award Article, Back Cover)

  63. Radical C-H Functionalization of Heteroarenes under Electrochemical Control
  64. A. O'Brien, A. Maruyama, Y. Inokuma, M. Fujita, P. S. Baran, D. G. Blackmond

    Angew. Chem. Int. Ed. 2014, 53, 11868-11871.

    (Selected as a Hot Paper)

  65. X-ray Snapshot Observation of Palladium-Mediated Aromatic Bromination in a Porous Complex
  66. K. Ikemoto, Y. Inokuma, K. Rissanen, M. Fujita

    J. Am. Chem. Soc. 2014, 136, 6892-6895.

    (Highlighted by "Chemistry World", RSC)

  67. Preparation and Guest-uptake Protocol for a Porous Complex Useful for 'Crystal-free' Crystallography
  68. Y. Inokuma, S. Yoshioka, J. Ariyoshi, T. Arai, M. Fujita

    Nature Protocols 2014, 9, 246-252.

  69. Stable Encapsulation of Acrylate Esters in Networked Molecular Capsules
  70. G.-H Ning, Y. Inokuma, M. Fujita

    Chem. Asian J. 2014, 9, 466-468.

    (VIP paper, Inside Cover)

  71. Unique Ultrafast Energy Transfer in a Series of Phenylene-bridged Subporphyrin-porphyrin Hybrids
  72. J. Oh, J. Sung, M. Kitano, Y. Inokuma, A. Osuka, D. Kim

    Chem. Commun. 2014, 50, 10424-10426.

  73. Dynamic Behavior of M6L4 Capsules in Solution and Crystalline States
  74. G.-H Ning, Y. Inokuma, M. Fujita

    Chem. Asian J. 2013, 8, 2596-2599.

  75. X-ray analysis on the nanogram to microgram scale using porous complexes
  76. Y. Inokuma, S. Yoshioka, J. Ariyoshi, T. Arai, Y. Hitora, K. Takada, S. Matsunaga, K. Rissanen, M. Fujita

    Nature 2013, 495, 461-466.

    (Highlighted by "Nature news and views" )

    (Highlighted by "C&EN", ACS)

    (Highlighted by "Chemistry World", RSC)

  77. Reagent-Installed Capsule Network: Selective Thiocarbamoylation of Aromatic Amines in Crystals with Pre-installed CH3NCS
  78. Y. Inokuma, G.-H. Ning, M. Fujita

    Angew. Chem. Int. Ed. 2012, 51, 2379-2381.

  79. Oxocyclohexadienylidene-Substituted Subporphyrins
  80. S. Hayashi, J. Sung, Y. Sung, Y. M. Sung, Y. Inokuma, D. Kim, A. Osuka

    Angew. Chem. Int. Ed. 2011, 50, 3253-3256.

  81. Bimolecular Reaction via the Successive Introduction of Two Substrates into the Crystals of Networked Molecular Cages
  82. Y. Inokuma, N. Kojima, T. Arai, M. Fujita

    J. Am. Chem. Soc. 2011, 133, 19691-19693.

  83. Diels-Alder via Molecular Recognition in a Crystalline Molecular Flask
  84. K. Ikemoto, Y. Inokuma, M. Fujita

    J. Am. Chem. Soc. 2011, 133, 16806-16808.

  85. Shedding Light on Hidden Reaction Pathways in Radical Polymerization by a Porous Coordination Network
  86. Y. Inokuma, S. Nishiguchi, K. Ikemoto, M. Fujita

    Chem. Commun. 2011, 47, 12113-12115.

  87. Synthesis and Properties of Boron(III)-Coordinated Subbacteriochlorins
  88. S. Hayashi, E. Tsurumaki, Y. Inokuma, P. Kim, Y. M. Sung, D. Kim, A. Osuka

    J. Am. Chem. Soc. 2011, 133, 4254-4256.

  89. Crystalline Molecular Flasks
  90. Y. Inokuma, M. Kawano, M. Fujita

    Nature Chem. 2011, 3, 349-358.

  91. A Molecular Capsule Network: Guest Encapsulation and Control of Diels-Alder Reactivity
  92. Y. Inokuma, S. Yoshioka, M. Fujita

    Angew. Chem. Int. Ed. 2010, 49, 8912-8914.

  93. Networked Molecular Cages as Crystalline Sponges for Fullerenes and Other Guests
  94. Y. Inokuma, T. Arai, M. Fujita

    Nature Chem. 2010, 2, 780-783.

    (Highlighted by "C&EN", ACS)

  95. The Reaction of Organozinc Compounds with an Aldehyde within a Crystalline Molecular Flask
  96. K. Ikemoto, Y. Inokuma, M. Fujita

    Angew. Chem. Int. Ed. 2010, 49, 5750-5752.

  97. The Catalytic Z to E Isomerization of Stilbenes in a Photosensitizing Porous Coordination Network
  98. K. Ohara, Y. Inokuma, M. Fujita

    Angew. Chem. Int. Ed. 2010, 49, 5507-5509.

  99. Regioselective Huisgen Cycloaddition within Porous Coordination Networks
  100. T. Kawamichi, Y. Inokuma, M. Fujita

    Angew. Chem. Int. Ed. 2010, 49, 2375-2377.

    (Highlighted by "Noteworthy Chemistry", ACS)

  101. A Porous Coordination Network Catalyzes an Olefin Isomerization Reaction in the Pore
  102. K. Ohara, M. Kawano, Y. Inokuma, M. Fujita

    J. Am. Chem. Soc. 2010, 132, 30-31.

  103. meso-Tris(oligo-2,5-thienylene)-Substituted Subporphyrins
  104. S. Hayashi, Y. Inokuma, A. Osuka

    Org. Lett. 2010, 12, 4148-4151.

  105. meso-Trifluoromethyl-substituted Subporphyrin from Ring-splitting Reaction of meso-Trifluoromethyl-substituted [32]Heptaphyrin(1.1.1.1.1.1.1)
  106. R. Sakamoto, S. Saito, S. Shimizu, Y. Inokuma, N. Aratani, A. Osuka

    Chem. Lett. 2010, 39, 439-441.

  107. meso-Trialkyl-substituted Subporphyrins
  108. S. Hayashi, Y. Inokuma, S. Easwaramoorthi, K. S. Kim, D. Kim, A. Osuka

    Angew. Chem. Int. Ed. 2010, 49, 321-324.

  109. Versatile Photophysical Properties of meso-Aryl Substituted Subporphyrins: Dipolar and Octupolar Charge-Transfer Interactions
  110. S. Easwaramoorthi, J.-Y. Shin, S. Cho, P. Kim, Y. Inokuma, E. Tsurumaki, A. Osuka, D. Kim

    Chem. Eur. J. 2009, 15, 12005-12017.

  111. Capped Subporphyrins
  112. Y. Inokuma, A. Osuka

    Chem. Eur. J. 2009, 15, 6863-6876.

  113. 1,4-Phenylene-bridged Subporphyrin-porphyrin Dyad, Triad, and Tetrad
  114. Y. Inokuma, S. Hayashi, A. Osuka

    Chem. Lett. 2009, 38, 206-207.

  115. Peripheral Hexabromination, Hexaphenylation, and Hexaethynylation of meso-Aryl- Substituted Subporphyrins
  116. E. Tsurumaki, Y. Inokuma, S. Easwaramoorthi, J. M. Lim, D. Kim, A. Osuka

    Chem. Eur. J. 2009, 15, 237-247.

  117. 3,3- and 4,4-Biphenylene-Bridged Subporphyrin Dimers
  118. Y. Inokuma, A. Osuka

    Org. Lett. 2008, 10, 5561-5564.

  119. Unambiguous Identification of Möbius Aromaticity for meso-Aryl-Substituted [28]Hexaphyrins(1.1.1.1.1.1)
  120. J. Sankar, S. Mori, S. Saito, H. Rath, M. Suzuki, Y. Inokuma, H. Shinokubo, K. S. Kim, Z. S. Yoon, J.-Y. Shin, J. M. Lim, Y. Matsuzaki, O. Matsushita, A. Muranaka, N. Kobayashi, D. Kim A. Osuka

    J. Am. Chem. Soc. 2008, 130, 13568-13579.

  121. meso-(4-(N,N-Dialkylamino)phenyl)-Substituted Subporphyrins: Remarkably Perturbed Absorption Spectra and Enhanced Fluorescence by Intramolecular Charge Transfer Interactions
  122. Y. Inokuma, S. Easwaramoorthi, Z. S. Yoon, D. Kim, A. Osuka

    J. Am. Chem. Soc. 2008, 130, 12234-12235.

  123. Effective Expansion of the Subporphyrin Chromophore Through Conjugation with meso-Oligo(1,4-phenyleneethynylene) Substituents: Octupolar Effect on Two-Photon Absorption
  124. Y. Inokuma, S. Easwaramoorthi, S. Y. Jang, K. S. Kim, D. Kim, A. Osuka

    Angew. Chem. Int. Ed. 2008, 47, 4840-4843.

  125. Subporphyrins: Emerging Contracted Porphyrins with Aromatic 14π-Electronic Systems and Bowl-Shaped Structures: Rational and Unexpected Synthetic Routes
  126. Y. Inokuma, A. Osuka

    Dalton Trans. 2008, 2517-2526. (Perspective, Front Cover)

  127. Synthesis and Characterization of meso-Aryl-Substituted Subchlorins
  128. E. Tsurumaki, S. Saito, K. S. Kim, J. M. Lim, Y. Inokuma, D. Kim, A. Osuka

    J. Am. Chem. Soc. 2008, 130, 438-439.

  129. Complementary Face-to-Face Dimer Formation From meso-Aryl Subporphyrins Bearing a 2-Carboxyphenyl Group
  130. Y. Inokuma, A. Osuka

    Chem. Commun. 2007, 2938-2940.

  131. meso-Aryl-Substituted Subporphyrins: Synthesis, Structures, and Large Substituent Effects on Their Electronic Properties
  132. Y. Inokuma, Z. S. Yoon, D. Kim, A. Osuka

    J. Am. Chem. Soc. 2007, 129, 4747-4761.

  133. Tribenzosubporphines: Synthesis and Characterization
  134. Y. Inokuma, J. H. Kwon, T. K. Ahn, M.-C. Yoon, D. Kim, A. Osuka

    Angew. Chem. Int. Ed. 2006, 45, 961-964.

  135. Enlarged π-Electronic Network of a meso-meso, β-β, β-β Triply Linked Dibenzoporphyrin Dimer that Exhibits a Large Two-Photon Absorption Cross Section
  136. Y. Inokuma, N. Ono, H. Uno, D. Y. Kim, S. B. Noh, D. Kim, A. Osuka

    Chem. Commun. 2005, 3782-3784.

  137. A Doubly N-Fused Benzohexaphyrin and Its Rearrangement to a Fluorescent Macrocycle upon DDQ Oxidation
  138. Y. Inokuma, T. Matsunari, N. Ono, H. Uno, A. Osuka

    Angew. Chem. Int. Ed. 2005, 44, 1856-1860.

  139. meso-Porphyrinyl-Substituted Porphyrin and Expanded Porphyrins
  140. Y. Inokuma, A. Osuka

    Org. Lett. 2004, 6, 3663-3666.