Hiroaki EIDA / M2
- TEL： +81-11-706-5587
Research topic
Aminoglycoside antibiotics resistance within Escherichia coli biofilms
Research abstract
Bacteria form biofilms under various environmental conditions and cells in biofilms are considered to be highly resistant to antibiotics compared to planktonic cells. In addition, subinhibitory stresses induce biofilm formation. Several mechanisms have been proposed to explain this high resistance. However it is still difficult to fully understand the mechanisms of biofilm resistance to antibiotics. In this study, we focused on previously-uncharacterized genes, which are considered to be related to aminoglycoside resistance in Escherichia coli, and investigated the association of these genes with antibiotic resistance and biofilm formation.
